This is Part 2 of my two part introduction to Jett Plasma technology. Watch last week’s Part 1 first. Now available in the USA (Dan Wray: danwray64@icloud.com).
Low-level direct current (DC) can have various effects on skin, tissues, and nerves, which are important for both therapeutic applications and understanding the biological response to electrical stimulation. Here’s a detailed explanation of the Plasmaporation effects using DC current.
Red Alinsod, MD (red@gynflix.com)
What is Plasma
The Jett Plasma device, manufactured by Compex in the Czech Republic, utilizes a unique plasma technology for skin treatments. Here's an overview based on available information:
Plasma is often referred to as the fourth state of matter, following solids, liquids, and gases. It consists of a gas that has been ionized, meaning it contains free electrons and ions which give it unique properties. Plasma can conduct electricity and is affected by magnetic fields, making it a versatile medium for various applications, including medical treatments.
How is Plasma Generated in the Jett Plasma Device?
Direct Current (DC) Plasma Generation: The Jett Plasma device uses DC voltage to generate plasma. This method involves creating spark discharges that produce heat. The technology is based on DC fulguration, which is more precise than alternating current (AC) methods because it affects a smaller area of the skin and doesn't damage surrounding tissues.
Mechanism: Plasma is generated between the device's tip and the patient's skin which is conductively connected to the device. The tip is held about 2 mm above the skin, and the high-energy discharge ionizes the air, turning it into plasma. This plasma discharge does not touch the skin but generates a thermal effect on the surface and subsurface layers.
Effects on Skin:
Skin Tightening and Lifting: The heat from the plasma stimulates the body's natural healing response, leading to collagen production. This results in skin tightening and a lifting effect, particularly effective for areas like the eyelids for non-surgical blepharoplasty.
Collagen Production: The thermal effect induces immediate skin tightening and promotes long-term collagen synthesis, which can reduce wrinkles, fine lines, and improve skin texture.
Treatment of Skin Imperfections: It's used for non-surgical treatment of various skin conditions including moles, skin tags, warts, and even scars. The plasma energy can sublimate skin lesions without cutting, providing an alternative to traditional surgery.
Minimal Downtime: The Jett Plasma treatment is noted for its minimal downtime compared to surgical options. While there might be some temporary redness, swelling, or crusting, these effects are generally less severe and shorter-lasting than those from surgical procedures.
Versatility: The device can be used in dermatology, aesthetic medicine, non-invasive surgery, ophthalmology, and other medical fields for a range of treatments from skin rejuvenation to lesion removal.
Safety and Precision: Being a non-contact method, it reduces the risk of scarring and infection, provided the procedure is carried out by trained professionals under appropriate conditions.
The effectiveness and safety of Jett Plasma treatments are highlighted in various medical studies and applications, indicating its significance in modern skin care and cosmetic procedures.
Effects of Low-Level DC Current
1. Plasmaporation Skin Effects:
Electrochemical Reactions: When DC current passes through the skin, it can induce electrochemical reactions at the electrode-skin interface. This can lead to the formation of alkaline or acidic environments depending on the polarity of the electrodes, which may cause skin irritation or burns if not carefully monitored.
Vasodilation: DC current can induce vasodilation (widening of blood vessels) due to the release of histamines and other mediators such as heat. This can improve blood circulation in the area, promoting healing.
Increased Permeability: The passage of low-level DC can increase skin permeability, which may enhance the absorption of topical medications.
2. Tissue Effects:
Thermal Effects: Low-level DC can generate heat in the tissues due to resistance. While this effect can be beneficial for promoting healing, excessive heat can lead to tissue damage. Jett Plasma maxes out at a safe 40-42 Celsius. Skin burns begin at 55 Celsius.
Stimulation of Cellular Activity: DC can promote cellular activities such as migration, proliferation, and differentiation. This is particularly relevant in wound healing and tissue repair and regeneration.
Electroporation: One of the significant effects of low-level DC is the phenomenon known as electroporation (also known as Plasmaporation, Predictive Permeation, ,Dermoelectroporation/DEP). Specialized and tested software allows safe and comfortable use and passage of nutrients and proteins into the cell.
Electroporation is seen with DC Current and not AC Current
Definition: Electroporation refers to the process of creating temporary pores in cell membranes through the application of electric fields. This phenomenon allows for increased permeability of the cell membrane to various substances, including drugs, genes, and other macromolecules.
1. Mechanism of Plasmaporation:
When a sufficiently strong electric field is applied across a cell membrane, it induces a charge imbalance, leading to structural changes in the lipid bilayer. These changes create transient pores, allowing substances that normally cannot pass through the membrane to enter the cell.
The size and duration of these pores depend on the strength and duration of the applied DC current.
2. Applications in Medicine:
Drug Delivery: Electroporation can enhance the delivery of therapeutic agents into cells, making it a promising technique for gene therapy, cancer treatment, and vaccine delivery. This is particularly useful for delivering large molecules like plasmid DNA.
Tissue Engineering: It can be used to facilitate the incorporation of growth factors or other bioactive molecules into scaffolds used in tissue engineering.
Cancer Treatment: Research is ongoing into the use of electroporation in combination with chemotherapeutic agents to increase the efficacy of treatment while reducing systemic side effects.
3. Safety and Considerations:
While electroporation can be beneficial, it must be carefully controlled to avoid cell death or damage to surrounding tissues. The parameters such as current intensity, duration, and frequency must be optimized for each application.
DC v AC Current
Direct Current (DC) vs. Alternating Current (AC)
1. Nature of Current:
Direct Current (DC): Flows in one direction steadily. The voltage remains constant over time.
Alternating Current (AC): Changes direction periodically. The voltage varies sinusoidally with time, typically at a frequency of 50 or 60 Hz.
Radiofrequency devices use AC. No electroporation.
2. Physiological Responses:
DC:
Skin Response: Electroporation. Can cause a stronger electrochemical reaction at the electrodes, leading to potential burns or irritation if the current is too high. Specialized software is used to precisely regulate the milliampere energy for comfort and speed of poration.
Tissue Response: Can stimulate muscle contractions and may cause localized heating stimulating the healing cascade.
AC:
Skin Response: Generally produces a more uniform sensation. The alternating nature can prevent tissue damage compared to DC.
Tissue Response: Often used for pain relief and muscular stimulation; can induce deeper tissue effects without as much discomfort.
No electroporation.
3. Medical Applications:
DC:
Used in electrotherapy for treatments like galvanic stimulation, which can enhance drug delivery through iontophoresis or stimulate nerve and muscle tissues.
Utilized in certain diagnostic tests and in some medical devices like pacemakers.
AC:
Commonly used in TENS (Transcutaneous Electrical Nerve Stimulation) units for pain relief.
Employed in muscle stimulators and for various rehabilitation therapies.
AC is also used in diagnostic imaging and certain types of monitoring equipment.
Summary
In summary, the choice between DC and AC in medical applications depends on the desired physiological effect, as well as safety and comfort considerations for the patient.
Low-level DC current has significant effects on skin, tissues, and nerves, including electrochemical reactions, increased permeability, and stimulation of cellular activity. Electroporation, induced by DC current, presents a valuable technique for enhancing drug delivery and tissue engineering applications. Understanding these effects is crucial for the safe and effective use of electrical stimulation in medical practice.
PROTOCOL FOR JETT PLASMA
For more information contact Distributor: Dan Wray: danwray64@icloud.com
Pre-Congress Sign Ups are Open for the Annual ISCG Congress 2025!
If you have not been to an ISCG Congress then you must attend ISCG 2025. Plan ahead for for March 20-22, 2025 in Fort Lauderdale. Lots of amazing topics and world leaders to present them. Meet and speak with the BEST.
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